PUBLICATIONS

“The joy of discovery is certainly the liveliest that the mind can ever feel”

- Claude Bernard -

1. Davidson, J. N. and NISWANDER, L. A. (1983). Partial cDNA sequence to a hamster gene corrects defect in Escherichia coli pyrB mutant. Proc. Natl. Acad. Sci. USA 80: 6897-6901. PMCID: PMC390093

2. Rumsby, P. C., Campbell, P. C., NISWANDER, L. A. and Davidson, J. N. (1984). Organization of a mutifunctional protein in pyrimidine biosynthesis. Biochemical Journal 217: 435-440. PMCID: PMC1153234

3. Patterson, D., Vannais, D. B., NISWANDER, L. A. and Davidson, J. N. (1985) Identification and localization of DNA alteration in Chinese hamster ovary cell mutants (Urd-) defective in the first three enzymes of de novo pyrimidine synthesis. Somatic Cell and Molecular Genetics 11: 379-390. PMID: 2992101

4. Davidson, J. N., Rumsby, G. and NISWANDER, L. A. (1985). Expression of genes on human chromosome 21. Annals of the New York Academy of Sciences 450: 43-54. PMID: 2409886

5. Shigesada, K., Stark, G. R. Maley, J. A., NISWANDER, L.A. and Davidson, J. N. (1985). Construction of a cDNA to the hamster CAD gene and its application toward defining the domain for aspartate transcarbamylase. Molecular and Cellular Biology 5: 1735-1742. PMCID: PMC367292

6. NISWANDER, L. A., Yee, D., Rinchik, E. M., Russell, L. B. and Magnuson, T. (1988). The albino deletion complex and early postimplantation survival in the mouse. Development 102: 45-53. PMID: 3416773

7. NISWANDER, L.A., Yee, D., Rinchik, E. M., Russell, L. B. and Magnuson, T. (1989). The albino-deletion complex in the mouse defines genes necessary for development of embryonic and extraembryonic ectoderm. Development 105: 175-182. PMID: 2806116

8. NISWANDER, L.A., Edström, J.-E., Rinchik, E. M. and Magnuson, T. (1989). Genetics of early embryo survival. In: Transgenic Models in Medicine and Agriculture, ed. R. Church, (Alan R. Liss, Inc., New York).

9. Davidson, J. N., Gadiparthi, N. R., NISWANDER, L., Andreano, C., Tamer, C., and Chen, K.-C. (1990). Organization and nucleotide sequence of the 3' end of the human CAD gene. DNA and Cell Biology 9: 667-676. PMID: 1979741

10. NISWANDER, L. A., Kelsey, G., Schedl, A., Ruppert, S., Sharan, S. K., Holdener-Kelly, B., Rinchik, E., M., Edström, J.-E., and Magnuson, T. (1991). Molecular mapping of albino deletions associated with early embryonic lethality in the mouse. Genomics 9: 162-169. PMID: 2004758

11. Hollingsworth, Jr., R. E., Ostroff, R. M., Klein, M. B., NISWANDER, L. A, and Sclafani, R. A. (1992). Molecular genetic studies of Cdc7 protein kinase and induced mutagenesis in yeast. Genetics 132, 53-62. PMCID: PMC1205129

12. Kelsey, G., Schedl, A., Ruppert, S., Klebig, M.L., NISWANDER, L., Magnuson, T., Rinchik, E.M., and Schütz, G. (1992). Physical mapping of alf/hsdr-1, a locus defined by albino deletion complex of mouse required for neonatal survival. Genomics 14, 275-287. PMID: 1427844

13. Schedl, A., Ruppert, S., Kelsey, G., Thies, E., NISWANDER, L., Magnuson, T., Klebig, M.L., Rinchik, E.M., and Schütz, G. (1992). Chromosome jumping from flanking markers define a minimal region for alf/hsdr-1 within the albino-deletion complex. Genomics 14, 288-297. PMID: 1427845

14. NISWANDER, L. and Martin, G.R. (1992). Fgf-4 expression during gastrulation, myogenesis, limb and tooth development in the mouse. Development 114: 755-768. PMID: 1618140

15. NISWANDER, L. and Martin, G.R. (1993). FGF-4 and BMP-2 have opposite effects on limb growth. Nature 361, 68-71. PMID: 8421496

16. NISWANDER, L. and Martin, G.R. (1993). FGF-4 regulates expression of Evx-1 in the developing limb. Development 119, 287-294. PMID: 7506139

17. NISWANDER, L., Tickle, C., Vogel, A., Booth, I., and Martin, G.R. (1993). FGF-4 replaces the apical ectodermal ridge and directs outgrowth and patterning of the limb. Cell 75, 579-587. PMID: 8221896

18. NISWANDER, L., Tickle, C., Vogel, A., Martin, G.R. (1994). Function of FGF-4 in Limb Development. Journal of Molecular Reproduction and Development 39: 83-89. PMID: 7999365

19. NISWANDER, L., Jeffrey, S., Martin, G.R., and Tickle, C. (1994). Positive feedback loop coordinates growth and patterning in the vertebrate limb. Nature 371, 609-612. PMID: 7935794

20. Yang, Y. and NISWANDER, L. (1995). Interaction between the signaling molecules WNT and SHH during vertebrate limb development: dorsal signals regulate anteroposterior patterning. Cell 80, 939-947. PMID: 7697724

21. Vogel, A., Roberts-Clarke, D. and NISWANDER, L. (1995). Effect of FGF on gene expression in chick limb bud cells in vivo and in vitro. Developmental Biology 171, 507-520. PMID: 7556932

22. Zou, H. and NISWANDER, L. (1996). Requirement for BMP signaling in interdigital apoptosis and scale formation. Science 272, 738-741. PMID: 8614838

23. NISWANDER, L. (1996). Growth factor interactions in limb development. Annals of the New York Academy of Sciences 785: 23-26. PMID: 8702137

24. Kuhlman, J. and NISWANDER, L. (1997). Limb deformity protein: Role in mesodermal induction of the apical ectodermal ridge. Development 124, 133-139. PMID: 9006074

25. Zou, H., Wieser, R., Massagué, J. and NISWANDER, L. (1997). Distinct roles of type I bone morphogenetic protein receptors in the formation and differentiation of cartilage. Genes and Development 11, 2191-2203. PMCID: PMC275391

26. Laufer, E., Pizette, S., Zou, H., Orozco, O.E., NISWANDER, L. (1997). BMP expression in duck interdigital webbing: a reanalysis. Science 278, 305. PMID: 9340773

27. Zou, H., Choe, K-M., Lu, Y., Massagué, J., and NISWANDER, L. (1997). BMP signaling and vertebrate limb development. Cold Spring Harbor Symposis on Quantitative Biology, Vol. LXII, 269-272. PMID: 9598360

28. Yang, Y., Drossopoulou, G., Chuang, P.T., Duprez, D., Marti, E., Bumcrot, D., Vargesson, N., Clarke, J., NISWANDER, L., McMahon, A. and Tickle, C. (1997). Relationship between dose, distance and time in Sonic Hedgehog-mediated regulation in the chick limb development. Development 124, 4393-4404. PMID: 9334287

29. Crowe, R., Henrique, D., Ish-Horowicz, D., and NISWANDER, L. (1998). A new role for Delta in cell fate decisions: patterning the feather array. Development 125, 767-775. PMID: 9435296

30. Crowe, R. and NISWANDER, L. (1998). Disruption of scale development by Delta-1 misexpression. Developmental Biology 195, 70-74. PMID: 9520325

31. Bushdid, P. B., Brantley, D. M., Yull, F. E., Blaeuer, G. L., Hoffman, L. H., NISWANDER, L., and Kerr, L. D. (1998). Inhibition of NF-kB activity results in disruption of the apical ectodermal ridge and aberrant limb morphogenesis. Nature 392, 615-618. PMID: 9560159

32. Varley, J. E., McPherson, C. E., Zou, H., NISWANDER, L. and Maxwell, G. D. (1998). Expression of a constitutively active type I BMP receptor using a retroviral vector promotes the development of adrenergic cells in neural crest cultures. Developmental Biology 196, 107-118. PMID: 9527884

33. Gibson-Brown, J., Agulnik, S.I., Silver, L.M., NISWANDER, L., and Papaioannou, V.E. (1998) Involvement of T-box genes Tbx2-Tbx5 in vertebrate limb specification and development. Development 125, 2499-2509. PMID: 9609833

34. Crowe, R., Zikherman, J. A. and NISWANDER, L. (1999). Delta-1 negatively regulates the transition from prehypertrophic to hypertrophic chondrocytes during cartilage formation. Development 126, 987-998. PMID: 9927599

35. Pizette, S. and NISWANDER, L. (1999). BMPs negatively regulate structure and function of the limb apical ectodermal ridge. Development 126, 883-894. PMID: 9927590

36. Obara-Ishihara, T.*, Kuhlman, J.*, NISWANDER, L. and Herzlinger, D. (1999). The surface ectoderm is essential for nephric duct formation in intermediate mesoderm. Development 126, 1103-1108. (*, these authors contributed equally). PMID: 10021330

37. Pizette, S. and NISWANDER, L. (2000). BMPs are required at two steps of limb chondrogenesis: formation of prechondrogenic condensations and their differentiation into chondrocytes. Developmental Biology 219, 237-249. PMID: 10694419

38. Barna, M., Hawe, N., NISWANDER, L., Pandolfi, P. P. (2000). PLZF regulates limb and axial patterning. Nature Genetics 25, 166-172. PMID: 10835630

39. Pizette S. and NISWANDER L. (2001). Early steps in limb patterning and chondrogenesis. Novartis Foundation Symposium 232, 23-46. PMID: 11277083

40. Timmer, J., Johnson, J. and NISWANDER, L. (2001). The use of in ovo electroporation for the rapid analysis of neural-specific murine enhancers. Genesis 29, 123-132. PMID: 11252053

41. Holmes, G. and NISWANDER, L. (2001). Expression of slit-2 and slit-3 during chick development. Developmental Dynamics 222, 301-307. PMID: 11668607

42. Pizette, S., Abate-Shen, C. and NISWANDER, L. (2001). BMP controls proximodistal outgrowth, via induction of the apical ectodermal ridge, and dorsoventral patterning in the vertebrate limb. Development 128, 4463-4474. PMID: 11714672

43. Timmer, J., Wang, C. and NISWANDER, L. (2002). BMP signaling patterns the dorsal and intermediate neural tube via regulation of Homeobox and Helix-Loop-Helix transcription factors. Development 129, 2459-2468. PMID: 11973277

44. Atit, R., Conlon, R.A. and NISWANDER, L. (2003). EGF signaling patterns the feather array by promoting the interbud fate. Developmental Cell 4, 231-40. PMID: 1258606

45. Liu, A., Li, J.Y.H, Bromleigh, C., Lao, Z., NISWANDER, L. and Joyner, A. (2003). FGF17b and FGF18 have different midbrain regulatory properties from FGF8b and activated FGF receptors. Development 130, 6175-6185. PMID: 14602678

46. Huangfu, D., Liu, A., Rakeman, A. S., Murcia, N. S., NISWANDER, L. and Anderson, K. V. (2003). Hedgehog Signaling in the Mouse Requires Intraflagellar Transport Proteins. Nature 426, 83-87. PMID: 14603322

47. Holmes, G. Crooijmare, R., Groenen, M., NISWANDER, L. (2003.) ALC (ADJACENT TO LMX1 IN CHICK) is a novel dorsal limb mesenchyme marker. Gene Expression Patterns 3, 735-741. PMID: 14643681

48. Rouzankina, I., Abate-Shen, C. and NISWANDER, L. (2004). Dlx genes integrate positive and negative signals during feather bud development. Developmental Biology 265, 219-233. PMID: 14697365

49. Niemann, S., Zhao, C., Pascu, F., Stahl, U., Aulepp, U., NISWANDER, L., Weber, J.L., Müller, U. (2004). Homozygous WNT3 mutation causes tetra-amelia in a large consanguineous family. American Journal of Human Genetics 74, 558-63. PMCID: PMC1182269

50. Chesnutt, C. and NISWANDER, L. (2004). Plasmid-based short-hairpin RNA interference in the chicken embryo. genesis 39, 73-78. PMID: 15170691

51. Chesnutt, C., Burrus, L. Brown, A.M.C., and NISWANDER, L. (2004). Coordinate regulation of neural tube patterning and proliferation by TGFb and WNT signaling. Developmental Biology 274, 334-337. PMID: 1538516

52. Cretekos CJ, Weatherbee SD, Chen CH, Badwaik NK, NISWANDER L, Behringer RR, Rasweiler JJ 4th. (2005). Embryonic staging system for the short-tailed fruit bat, Carollia perspicillata, a model organism for the mammalian order Chiroptera, based upon timed pregnancies in captive-bred animals. Developmental Dynamics 233, 721-738. PMID: 15861401

53. Liu, A., Wang, B., NISWANDER, L. (2005). Mouse Intraflagellar Transport proteins regulate both the activator and repressor functions of Gli transcription factors. Development 132, 3103-3111. PMID: 15930098

54. DiPaola,C.P; Farmer, J.C; Manova, K., NISWANDER, L.A. (2005). Molecular signaling in intervertebral disk development. Journal of Orthopaedic Research 23, 1112-9 PMID: 15936916

55. Timmer, J., Chesnutt, C. and NISWANDER, L. (2005). The Activin signaling pathway promotes differentiation of dI3 interneurons in the spinal neural tube. Developmental Biology 285, 1-10. PMID: 16039645

56. Barna, M., Pandolfi, P.P. and NISWANDER. L. (2005). Gli3 and Plzf cooperate in proximal limb patterning at early stages of limb development. Nature 436, 277-281. PMID: 16015334

57. Timmer, J., Manova, K., Anderson, K.V. and NISWANDER, L. (2005). Tissue morphogenesis and vascular stability require the Frem2 protein, product of the mouse myelencephalic blebs gene. Proc Natl Acad Sci U S A 102, 11746-11750. PMCID1183448

58. Dean, C.H., Miller, L-A., Smith, A.N., Dufort, D., Lang, R.A., and NISWANDER, L. (2005). Canonical Wnt signaling negatively regulates branching morphogenesis of the lung and lacrimal gland. Developmental Biology 286, 270-286. PMID: 16126193

59. Sears, K.E., Behringer, R.R., Rasweiler, J.J., and NISWANDER, L.A. (2006). The Development of Bat Flight: Morphological and Molecular Evolution of Bat Wing Digits. Proc Natl Acad Sci U S A 103, 6581-6586. PMCID: PMC1458926

60. Atit, R.P., Sgaier, S.K., Mohamed, O.A., Taketo, M.M., Dufort, D., Joyner, A.L., NISWANDER, L. and Conlon, R.A. (2006). Beta-catenin activation is necessary and sufficient to specify the dorsal dermal fate in the mouse. Developmental Biology 296, 164-176. PMID: 16730693

61. Zohn, I.E., Li, Y., Skolnik, E.Y., Anderson, K.V., Han, J. and NISWANDER, L. (2006). p38 and a p38-interacting protein are critical regulators of E-cadherin downregulation during mouse gastrulation. Cell 125, 957-969. PMID: 16751104

62. Weatherbee, S., Behringer, R.R., Rasweiler, J.J. and NISWANDER, L. (2006). Interdigital webbing retention in bat wings illustrates genetic changes underlying amniote limb diversification. Proc Natl Acad Sci U S A 103, 15103-15107. . PMCID: PMC1622783

63. Weatherbee, S.D., Anderson, K.V. and NISWANDER, L.A. (2006). LDL-receptor-related protein 4 is critical for formation of the neuromuscular junction. Development 133, 4993-5000. PMID: 17119023

64. Sears, K.E., Behringer, R.R., Rasweiler, J.J. IV, and NISWANDER, L.A. (2007). The evolutionary and developmental basis of parallel reduction in mammalian zeugopod element. The American Naturalist 169, 105-117. PMID: 17206589

65. Zohn, I.E., De Domenico, I., Pollock, A., McVey Ward, D., Goodman, J.F., Liang, X., Sanchez, A.J., NISWANDER, L., and Kaplan, J. (2007). The flatiron mutation in mouse ferroportin acts as a dominant negative to cause ferroportin disease. Blood 109, 4174-4180. PMCID: PMC1885502

66. Zohn, I.E., Anderson, K.V., and NISWANDER, L. (2007). The Hectd1 Ubiquitin Ligase is Required for Development of the Head Mesenchyme and Neural Tube Closure. Developmental Biology 306, 208-221. PMCID: PMC2730518

67. Kim, T-H., Goodman, J., Anderson, K.V. and NISWANDER, L. (2007). Phactr4 regulates neural tube closure by controlling PP1, Rb phosphorylation and cell cycle progression. Developmental Cell 13, 87-102. PMID: 17609112

68. Barna, M. and NISWANDER, L. (2007). Visualization of cartilage formation: insight into cellular properties of skeletal progenitors and chondrodysplasia syndromes. Developmental Cell 12, 931-941. PMID: 17543865

69. Sears, K.E., Goswami, A., Flynn, J.J. and NISWANDER, L. (2007). The correlated evolution of Runx2 tandem repeats, transcriptional activity and facial length in Carnivora. Evolution and Development 9, 555-565. PMID: 17976052

70. Hoover, A.M., Wynkoop, A., Zeng, H., Jia, J., NISWANDER, L.A. and Liu, A. (2008). C2cd3 is required for cilia formation and Hedgehog signaling in the mouse.  Development 135, 4049-4058. PMCID312004471.

71.  Weatherbee, S.D., NISWANDER, L.A., and Anderson, K.V. (2009). A mouse model for Meckel Syndrome reveals Mks1 is required for ciliogenesis and Hedgehog signaling. Human Molecular Genetics 18, 4565-75. PMCID2773271

72. Hubler, M., NISWANDER, L., Peters, J. and Sears, K. (2010). The developmental reduction of the marsupial coracoid: A case study in Monodelphis domestica. Journal of Morphology 271, 769-76. PMID: 20151407

73. Pyrgaki, C., Trainor, P., Hadjantonakis, A.-K. and NISWANDER, L. (2010). Dynamic Imaging of Mammalian Neural Tube Closure. Developmental Biology 344, 941-94. PMID: 20558153, PMCID:PMC3873863

74. Yates, L.L., Schnatwinkel, C., Murdoch, J.N., Bogani, D., Formstone, C.J., Townsend, S., Greenfield, A., NISWANDER, L.A., and Dean, C.H. (2010). The PCP genes Celsr1 and Vangl2 are required for normal lung branching morphogenesis. Human Molecular Genetics 19, 2251-67. PMCID: PMC2865378

75. Mao, J., McKean, D.M., Warrier, S. Corbin, J.G., NISWANDER, L. and Zohn, I.E. (2010). The Iron Exporter Ferroportin1 is Essential for Development of the Mouse Embryo, Forebrain Pattering and Neural Tube Closure. Development 137, 3079-88. PMCID2926957

76. Becker-Heck, A.#, Zohn, I,#, Okabe, N.#, Pollock, A#, Baker, K., Sullivan-Brown, J., McSheene, J., Loges, N.T., Olbrich, H., Haeffner, K., Fliegauf, M., Horvath, J., Reinhardt, R., Nielsen, K.G., Marthin, J.K., Baktai, G., Geisler, R., NISWANDER, L., Omran, H., Burdine, R.D. (2011). The novel coiled-coil domain containing protein CCDC40 is essential for motile cilia function and left-right axis formation. Nature Genetics 43, 79-84. PMCID3132183

77.  Pyrgaki, C., Liu, A., and NISWANDER, L. (2011). Grainyhead-like 2 regulates neural tube closure and adhesion molecule expression during neural fold fusion. Developmental Biology 353, 38-49. PMCID3114429

78. Marean, A., Graf, A., Zhang, Y. and NISWANDER, L. (2011). Folic acid supplementation can adversely affect murine neural tube closure and embryonic survival. Human Molecular Genetics 20, 3678-83. PMCID3159553

79. Zhang, Y., Kim, T-H. and NISWANDER, L. (2012). Phactr4 coordinates directional migration of Enteric Neural Crest Cells through β1 integrin signaling. Genes & Development 1, 69-81. PMCID3258968

80.  Chen, J., Lai, F. and NISWANDER, L. (2012). The ubiquitin ligase mLin41 temporally promotes neural progenitor cell maintenance through FGF signaling. Genes & Development 26, 803-815. PMCID3337455

81.  Schnatwinkel, C and NISWANDER, L. (2012). Nubp1 is required for lung branching morphogenesis and distal progenitor cell survival in mice. PLoS One. 2012;7(9):e44871. PMID: 23028652

82.  McKean, D. and NISWANDER, L. (2012). Defects in GPI Biosynthesis Perturb Cripto Signaling During Forebrain Development in Two New Mouse Models of Holoprosencephaly. Biology Open 1:874-883. PMCID3507239

83.  Massarwa, R. and NISWANDER, L. (2013). In Toto Live Imaging of Mouse Morphogenesis and New Insights into Neural Tube Closure. Development Jan;140(1):226-36. PMCID3514000

84.  Yates, L., Schnatwinkel, C., Hazelwood, L., Chessum, L., Paudyal, A., Hilton, H., Romero, R., Wilde, J., Bogani, D., Sanderson, J., Formstone, C., Murdoch, J.N., NISWANDER, L.A., Greenfield, A., Dean, C. (2013). Scribble is required for normal epithelial cell-cell contacts and lumen morphogenesis in the mammalian lung. Developmental Biology Jan 15;373(2):267-80. PMCID: PMC3549499

85.  Zhang, Y. and NISWANDER, L. (2013). Zic2 is required for enteric nervous system development and neurite outgrowth: a mouse model of enteric hyperplasia and dysplasia. Neurogastroenterol Motil. 2013 Jun;25(6):538-41. doi: 10.1111/nmo.12101. PMID: 23413832, PMCID:PMC3862053

86.  Schnatwinkel, C. and NISWANDER, L. (2013). Multiparametric image analysis of lung branching morphogenesis. Developmental Dynamics Jun;242(6):622-37.doi: 10.1002/dvdy.23961. PMCID: PMC3833092

87.  Parker, J.J, Dionne, K.R., Massarwa, R., Klaassen, M., Foreman, N.K., NISWANDER, L., Canoll, P. Kleinschmidt-DeMasters, B.K. Waziri, A. (2013).  Gefitinib selectively inhibits tumor cell migration in EGFR-amplified human glioblastoma. Neuro Oncol. 8:1048-57. PMCID: PMC3714155; PMCID:PMC3714155

88.  Feng, W, Choi, I., Clouthier, D., NISWANDER, L. and Trevor Williams, T. (2013). The Ptch1DL mouse: a new model to study lambdoid craniosynosytsosis and basal cell nevus syndrome associated skeletal defects. Genesis. 2013 Oct;51(10):677-89. doi: 10.1002/dvg.22416. PMID: 23897749

89.   Harmacek, L., Watkins-Chow, D.E., Chen, J., Jones, K.L., Pavan, W.J., Salbaum, J.M. and NISWANDER, L. (2014). A unique missense allele of BAF155, a core BAF chromatin remodeling complex protein, causes neural tube closure defects in mice. Dev Neurobiol. 74(5):483-97. doi: 10.1002/dneu.22142. PMID: 24170322

90.   Chen, J., Zhang, Y., Wilde, J., Hansen, K., Lai, F., and NISWANDER, L. (2014). Microcephaly gene Wdr62 interacts with Aurora A/Tpx2 to regulate spindle stability and mitotic progression of neural stem cells. Nature Communications 5:3885. doi: 10.1038/ncomms4885  PMID: 24875059, PMCID: PMC4216695

91.    Hanson, M.G., Fregoso, V., Vrana, J.D., Tucker, C.L. and NISWANDER, L.A. (2014). Peripheral nervous system defects in a mouse model for peroxisomal biogenesis disorders.  Developmental Biology 395:84-95. doi: 10.1016/j.ydbio.2014.08.026    PMCID: PMC4190158

92.    Hanson, M.G. and NISWANDER, L.A. (2014). An explant muscle model to examine the refinement of the synaptic landscape. Journal of Neuroscience Methods 238C:95-104. doi:10.1016/j.jneumeth.2014.09.013

93.   Chang R, Petersen JR, NISWANDER LA, Liu A. A hypomorphic allele reveals an important role of Inturned in mouse skeletal development. Dev Dyn. 2015 Jun;244(6):736-47. doi: 10.1002/dvdy.24272. PMID: 25774014; PMCID: PMC4449324.

94.    Hanson, M. G., Wilde, J. J., Moreno, R. L., Minic, A. D., & NISWANDER, L. (2015). Potassium dependent rescue of a myopathy with core-like structures in mouse. eLife, 4. doi:10.7554/eLife.02923

95.   Yang, M., Yang, S.L., Herrlinger, S., Liang, C., Dzieciatkowska, M., Hansen, K.C., Desai, R., Nagy, A., NISWANDER, L., Moss, E.G., and Chen, J.F. (2015). Lin28 promotes the proliferative capacity of neural progenitor cells in brain development. Development 142, 1616-1627. doi: 10.1242/dev.120543. PMCID:

PMC4419280

96.   Hanson, M. G. and NISWANDER, L.A. (2015). Rectification of muscle and nerve deficits in paralyzed ryanodine receptor type 1 mutant embryos. Developmental Biology 404(2), 76–87. doi:10.1016/j.ydbio.2015.05.018

97.    Hanson, M.G., Aiken, J., Sept, D., NISWANDER, L.A., Bates, E., Moore, J. (2016). Novel α-tubulin mutation disrupts neural development and tubulin proteostasis. Developmental Biology 2016 Jan 15;409(2):406-19. doi: 10.1016/j.ydbio.2015.11.022. Epub 2015 Nov 30. PMID: 26658218

98.    Eric Van Otterloo, E. Feng, W., Jones, K.L., Hynes, N.E., Clouthier, D.E., NISWANDER, L., Williams, T. (2015). MEMO1 drives cranial endochondral ossification and palatogenesis. Developmental Biology 2015 Dec 31. pii: S0012-1606(15)30372-9. doi: 10.1016/j.ydbio.2015.12.024. [Epub ahead of print] PMID: 26746790

99.    Ray, H.J. and NISWANDER, L.A. (2016). Grainyhead-like 2 downstream targets act to suppress EMT during neural tube closure. Development. 143(7):1192-204. doi: 10.1242/dev.129825. PMID:26903501

100.  Ray, H.J. and NISWANDER, L.A. (2016). Dynamic Behaviors of the Non-Neural Ectoderm during Mammalian Cranial Neural Tube Closure. Developmental Biology 416(2):279-85. doi:10.1016/j.ydbio.2016.06.030. PMID:27343896

101.  Zhang, L., Ferreyros, M., Feng, W., Hupe, M., Crumrine, D.A., Chen, J., Elias, P.M., Holleran, W.M., NISWANDER, L., Hohl, D., Williams, T., Torchia, E.C., Roop, D.R. (2016). Defects in Stratum Corneum Desquamation Are the Predominant Effect of Impaired ABCA12 Function in a Novel Mouse Model of Harlequin Ichthyosis. PLoS ONE 11(8): e0161465. doi:10.1371/journal. pone.0161465

102. Wilde, J.J., Siegenthaler, J.A., Dent, S.Y.R., and NISWANDER, L.A. (2017). Diencephalic Size is Restricted by a Novel Interplay Between GCN5 Acetyltransferase Activity and Retinoic Acid Signaling. J Neurosci. 2017 Feb 2. pii: 2121-16. doi: 10.1523/JNEUROSCI.2121-16.2017. PMID: 28154153

103.  Li, H., Zhang, J., Chen, S., Wang, F., Zhang, T., NISWANDER, L. (2018). Genetic contribution of retinoid related genes to neural tube defects. Human Mutation. 2018 Apr;39(4):550-562. doi: 10.1002/humu.23397. Epub 2018 Jan 19.PMID:n29297599.

104. Baschal EE, Terhune EA, Wethey CI, Baschal RM, Robinson KD, Cuevas MT, Pradhan S, Sutphin BS, Taylor MRG, Gowan K, Pearson CG, Niswander LA, Jones KL, Miller NH. (2018).Idiopathic Scoliosis Families Highlight Actin-Based and Microtubule-Based Cellular Projections and Extracellular Matrix in Disease EtiologyG3 (Bethesda). 2018 Jul 31;8(8):2663-2672. doi: 10.1534/g3.118.200290.PMID: 29930198.

32. Zinc deficiency causes neural tube defects through attenuation of p53 ubiquitylation. Huili Li, Jing Zhang, Lee Niswander. Development 2018 145: dev169797 doi: 10.1242/dev.169797 Published 13 December 2018

 

Reviews and Book Chapters

1. NISWANDER, L. and Martin, G.R. (1993). Mixed Signals from the AER: FGF-4 and BMP-2 have Opposite Effects on Limb Growth. In Limb Development and Regeneration, Volume A & B. eds. Fallon, J., Kelley, R.O., Goetnick, P. and Stocum, D.L., (Wiley-Liss, New York).

2. NISWANDER, L. (1997). Limb mutants: what can they tell us about normal limb development? Current Opinion in Genetics and Development 7, 530-536. PMID: 9309186

3. NISWANDER, L. (1996). Molecular Control of Growth and Pattern Formation in the Developing Vertebrate Limb. In Mammalian Development, 135-150. ed. P. Lonai, (Harwood Academic Publishers).

4. NISWANDER, L. Vertebrate embryo: limb development. Encyclopedia of Life Sciences, article 728. (Macmillan Reference Limited, Stockton Press, London).

5. NISWANDER, L. (1999). Legs to wings and back again. Nature 389, 751-752. PMID: 10235252

6. NISWANDER, L. (2002). Interplay between the molecular signals that control vertebrate limb development. International Journal of Developmental Biology 46, 877-881. PMID: 12455624

7. NISWANDER, L. and Anderson, K. V. (2002). Hopeful monsters and morphogens at the beach. Nature Cell Biology 11, E259-262. PMID: 12415285

8. Liu, A., Wang, C. and NISWANDER, L. (2003). FGF signaling in vertebrate development. Encyclopedia of Life Sciences. (Macmillan Reference Limited, Stockton Press, London).

9. NISWANDER, L. (2003). Pattern Formation: old models out on a limb. Nature Reviews Genetics 4, 133-143. PMID: 1256081

10. Zohn, I. E., Chesnutt, C. R. and NISWANDER, L. (2003). Cell polarity pathways converge and extend to regulate neural tube closure. Trends in Cell Biology 13, 451-454. PMID: 12946622

11. Zohn, I.E., Anderson, K.V. and NISWANDER, L. (2005). Using genomewide mutagenesis screens to identify the genes required for neural tube closure in the mouse. Birth Defects Res A Clin Mol Teratology 73, 583-90. PMID: 15971254

12. Liu, A. and NISWANDER, L. (2005). Signalling in development: Bone Morphogenetic Proteins in Vertebrate Nervous System Development. Nature Reviews Neuroscience 6. 945-954. PMID: 16340955

13. Weatherbee, S.A and NISWANDER, L. (2007). Mechanisms of Chondrogenesis and Osteogenesis in Limbs, in Fins into Limbs. The University of Chicago Press, 93-102.

14. NISWANDER, L. (2008). Methods in avian embryology: experimental and molecular manipulation of the embryonic chick limb. Methods Cell Biol. 87, 135-52. PMID: 18485295

15. NISWANDER, L. and Bates, D. (2011). The Developmental Basis of Congenital Limb Differences (Chapter 174). In Fetal and Neonatal Physiology; editors R.A. Polin, W.W. Fox, and S.H. Abman

16. Ray, H.J. and NISWANDER, L. (2012). Mechanisms of Tissue Fusion during Development. Development 139, 1701-11.  PMCID: PMC3328173

17.  Zhang, Y and NISWANDER, L. (2012).  Phactr4: A new integrin modulator required for directional migration of enteric neural crest cells.  Cell Adhesion & Migration, 6(5). PMCID: PMC3496679

18.  Pyrgaki, C. and NISWANDER, L. (2013).  Neural Tube Defects (Chapter 41). Invited Chapter in Neural Circuit Development and Function in the Brain, Comprehensive Developmental Neuroscience series. ISBN: 978-0-12-397267-5

19.  Wallingford, J.B., NISWANDER, L.A., Shaw, G.M., Finnell, R.H. (2013). The continuing challenge of understanding and preventing neural tube defects. Science 339(6123):1222002.  PMCID: PMC3677196

20.  Massarwa, R., Ray, H. and NISWANDER, L. (2013). Morphogenetic movements in the neural plate and neural tube: Mouse. WIREs Dev Biol 2013. doi: 10.1002/wdev.120

21.  Sussel, L. and NISWANDER, L. (2014). Editorial overview: developmental mechanisms, patterning and evolution. Curr Opin Genet Dev. 2014 Aug;27:v-vii. doi: 10.1016/j.gde.2014.06.007  PMID: 24998023

22.  Apkon, S.D., Grady, R., Hart, S., Lee, A., McNalley, T., NISWANDER, L., Petersen, J. Remley, S., Rotenstein, D., Shurtleff, H., Warner, M., Wallder, W.O. (2014). Advances in the Care of Children with Spina Bifida. Invited chapter: Genetics of Human Neural Tube Defects. Advances in Pediatrics 61, 33–74. PMID: 25037124 doi: 10.1016/j.yapd.2014.03.007

23.  Wilde, J.J.*, Petersen, J.P.* and NISWANDER, L.A. (2014). Genetic, epigenetic and environmental contributions to neural tube closure. Annual Review of Genetics 48:583-611. doi: 10.1146/annurev-genet-120213-092208

24. Niswander L. Forming and shaping the field of limb development: A tribute to Dr. John Saunders. Dev Biol. 2017 Sep 15;429(2):373. doi: 10.1016/j.ydbio.2017.08.020. No abstract available. PMID: 28864071.

25. Li, H., & Niswander, L. (2018). Does DNA methylation provide a link between folate and neural tube closure? Epigenomics. doi:10.2217/epi-2018-0116

26. Pyrgaki, C., Brown, H., Jaffe, E., Pezoa, SA, and Niswander, L. (2019).  Neural Tube Defects. Invited Chapter in Neurodevelopmental Disorders and Function in the Healthy and Diseased Brain book. Editor John L. R. Rubenstein.

 


 


 

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